Similac Pro Sensitive vs Total Comfort – Which Is Better?

By Maria Wilcox •  Updated: 09/20/22 •  12 min read
Hey Mamas and Papas! This site is reader-supported and we earn commissions if you purchase products from retailers after clicking on a link from our site.

If you’ve been formula feeding for any amount of time, you know how difficult it can be to pick the right Similac formula for your baby. Choosing between Similac Pro Sensitive vs Total Comfort (and a wide array of other Similac varieties) can make it difficult to know which is best for your baby’s needs. So, which is the best formula between the two? Read on to learn more information about the major differences between Similac Pro Sensitive vs Total Comfort. 

similac pro sensitive vs total comfort

Similac Pro Sensitive vs Total Comfort: Which to Choose?

When choosing between Similac Pro Sensitive and Similac Total Comfort you may have difficulty distinguishing which is which. Indeed, the two seem very similar. It’s almost as if they make the same claims! But the truth of the matter is that two are quite different even though they share many similarities. 

So, what are the major differences between them? We’re glad you asked! 

What Is Similac Total Comfort Used For?

Similac Total Comfort is described by Similac as the most gentle formula they offer. It is designed for the baby that experiences fussiness and gas, possibly due to the inability to digest milk proteins found in other formula blends. 

Similac Total Comfort Infant Formula, Imported, Easy-to-Digest Baby Formula Powder, Non-GMO, 820 g (28.9 oz) Can
Buy on Amazon

When it comes to milk proteins, babies can often have issues. Casein and whey are two major proteins found in milk. These two components can cause your baby gas, fussiness, and in some cases, constipation. 

With Similac Total Comfort, developers have done their best to remove the irritating elements of typical infant formula to produce something much gentler. By removing casein and hydrolyzing the whey, the formula is much easier digested by littles.

In fact, Similac claims Total Comfort formula eases gas and fussiness in babies in as little as one day. Not only this, but Similac Total Comfort also offers a blend of Lutein, DHA, and Vitamin E along with other beneficial ingredients to help your baby grow healthy and strong. 

Note: Similac Total Comfort and Similac Pro Total Comfort have very similar ingredients. The main difference is that the “Pro” version contains oligosaccharides while the other does not. The Pro version is also non-GMO. Depending on where you live, you may find only one Total Comfort option instead of both. It’ll be up to you and your doctor to decide which version is best for your little one and determine its availability near you.

Similac Pro Total Comfort Reviews

Parent reviews are the best reviews. So what are moms and dads saying about Total Comfort and Pro Total Comfort? Honestly, they love it.

Parents claim that this Pro Total Comfort has saved their baby’s tummy even after other Similac brands only seemed to be making matters worse. This is likely because Similac’s Total Comfort formula is the gentlest formulation they have. Therefore, it would make sense that out of all the types available, the Total Comfort is the one that provides the most relief to delicate tummies. 

What Is Similac Pro Sensitive Used For?

With all of the buzz surrounding Similac Total Comfort, you may be wondering about the differences between it and Similac Pro Sensitive. After all, Similac Sensitive should be for sensitive tummies, too, right? 

Honestly, the comparison can be a little frustrating. Similac’s website isn’t abundantly clear about the differences between the two, so we will do our best to highlight the differences for you.

First, Similac Pro Sensitive is advertised as reducing fussiness specifically related to lactose sensitivity. Unlike Similac Total Comfort, it does not claim to ease gas nor does it claim to ease fussiness in as little as one day.

All claims made in regards to Sensitive and Pro Sensitive deal with lactose sensitivity. However, if your baby is sensitive to casein, he or she is likely to still have issues with Similac Pro Sensitive. It is for this reason that we strongly recommend involving a doctor when picking the right formula. These finite details are crucial to keeping your baby comfortable and happy. 

Note: Know that all Similac “Pro” formulas contain oligosaccharides designed to mimic those found in human breast milk. These benefit your child. These formulas are also made non-GMO which is another advantage of buying Pro. 

similac pro sensitive vs total comfort

Similac Pro Sensitive Reviews

So, what’s the consensus when it comes to Similac Pro Sensitive reviews? Well, parents seem to either love it or hate it. As some parents sing the praises of Similac Pro Sensitive others claim it only made their baby’s symptoms worse. 

This is likely due to the differences in the makeup of the formula as one contains casein and the other does not. Babies with sensitivity to casein may not do well with Similac Sensitive Pro. Those who experience lactose sensitivity but can tolerate casein will likely do better with this formula. 

As always, please speak with your doctor for tailored advice. 

Similac Pro Sensitive vs Similac Pro Total Comfort

Now that we’ve broken down the major differences between the two formulas, here’s a brief recap and comparison of both Similac Pro Sensitive vs Similac Pro Total Comfort: 

Similac Pro Total ComfortSimilac Pro Sensitive
Claims to Be Good For Gasyesno
Claims to Relieve Symptoms in One Dayyesno
Claims to Be good For Fussinessyesyes
Cotains Caseinnoyes
Contains WheyYes-HydrolyzedYes
Contains Lutein, DHA, Vitamin Eyesyes
Provides Immune Supportyesyes
Contains Palm Olein Oilnono

Choosing the Best Formula For Your Baby

Now that you know whether or not Similac Pro Sensitive or Similac Total Comfort may work best for your baby, we want you to know the basics about selecting the very best Similac infant formula for your child. 

When it comes to Similac, you’ll notice you’ve got a plethora of options before you. Unfortunately, it can be very difficult to distinguish between formula types and the differences between them. Not only are many of the names the same, but many of these formulas seem to treat the same symptoms. So, what gives?

We understand and can totally relate to this issue. Consider taking the following steps before embarking on your journey to find out which baby formula is truly best for your baby. 

Identify Your Baby’s Needs

The very first step in selecting the right Similac formula is to identify your baby’s needs. When your baby is first born, you may not know which formula is right for your little one. In this case, you’ll need to do your research and prioritize the aspects of baby formula that are important to you. 

Ask yourself:

“Does the formula contain GMO?” 

“What are oligosaccharides and does this formula have any?”

“What are the effects of palm olein oil and do I want my baby consuming it?”

These are just a few of the questions you’ll want to ask before picking a formula for your unborn or previously breastfed baby. 

Once your baby has begun taking formula, you may notice that he or she has trouble with it. It may be that your baby begins to have constipation, gas, or uncontrollable fussiness. When these things crop up, it is important that you identify the source. Know that these issues can occur at any point during a formula-feeding journey. Even after they’ve been taking the formula for a long time! 

Thus, it is important to note the differences between formulas in order to know what might be causing your baby discomfort. 

Similac Pro Sensitive vs Total Comfort

Speak With Your Doctor

Before choosing an infant formula for your baby or switching your baby’s current formula, it is imperative that you speak with a doctor. This is particularly important if your baby is already on a formula and you wish to change it. By abruptly changing your baby’s formula without knowing the root cause of his or her discomfort, you may end up compounding the problem. 

For example, if you think your baby has gas due to something in his or her formula but you aren’t sure what, you may be tempted to switch formulas. However, it could be that your baby is dehydrated, is allergic to milk, or is stressed which could be underlying reasons he or she is having constipation and gas. Thus, switching formulas may or may not help remediate these issues. 

For this reason, it is imperative that alterations made to your baby’s formula feeding routine be done under the care and guidance of your local pediatrician.

Similac Pro Sensitive vs Total Comfort

Keep a Journal

If you’ve tried everything and nothing seems to be working, try keeping a journal. If your baby is particularly fussy at night, has frequent gas, is drawing their legs up to their chest, and screaming in pain, you must find the cause. It can help to write down what’s going on. Make note of at the time, how much formula they drank, and what type. 

It can also help to note how long ago they ate and what the conditions were surrounding his or her fussiness. Also, be sure to address other factors that may be going on before assuming it’s the formula. For example, make sure that your baby doesn’t need to be changed, isn’t sick, and isn’t hungry. 

Similac Pro Sensitive vs Total Comfort

Read the Claims

When it comes to actually choosing a new formula, you must be sure to thoroughly read the claims of the manufacturer. Each baby formula is different, and even those within the same brand can offer vastly different qualities. 

As previously mentioned, it is important that you know what characteristics of infant formula are important to you. If you’ve been taking note of your baby’s digestive issues in a journal, be sure to reference those when picking the best formula for your baby. There are formulas for lactose intolerance, colic, sensitive tummies, and more. Do your best to read the claims and reviews before deciding on one that may work for your child.

Similac Total Comfort Infant Formula, Imported, Easy-to-Digest Baby Formula Powder, Non-GMO, 820 g (28.9 oz) Can
Buy on Amazon

Stay Informed (By a Doctor)

Last but not least, be sure to consult your doctor before making a final switch. Though you may believe one infant formula may work best for your child, your doctor may provide you with additional information that may make you believe otherwise. Go with your doctor’s recommendations before acting on your own. This is especially important if you are tempted to switch formulas frequently. 

Switching formulas can be hard on your baby’s system as formulas are created so differently. Of course, we’d never recommend you buy something that is causing your baby trouble. But if you are unable to pin down the root cause and nothing seems to be working, you must involve your doctor. He or she will know the best course of action to take to get your baby feeling better. 

similac pro sensitive vs total comfort

Similac Pro Sensitive vs Total Comfort: Yes, There’s a Difference!

Though the differences between the two are hard to distinguish, there are several factors that make Similac Sensitive and Total Comfort different. 

Similac Pro Sensitive vs Total Comfort differ in terms of the presence of casein, which is known to irritate delicate tummies. In addition, Similac’s “Pro” line will automatically include oligosaccharides and non-GMO ingredients while basic formula versions, such as Similac Total Comfort, will not. 

Similac Pro Total Comfort can be found in select locations, including the US. However, the availability of all Similac products are subject to change. 

We hope this helps clear up any confusion surrounding these two very popular Similac formulas for babies with sensitivities. Until next time! 


 Did Similac discontinue Pro Total Comfort?

In some locations in the world, Similac Pro Total Comfort may or may not be available. The same is true of the Similac Total Comfort. 

Is Similac Pro Total Comfort lactose free?

Similac does not claim Similac Pro Total Comfort to be completely lactose-free. It does, however, claim the formula to be suitable for those with lactose sensitivities.

What’s the difference between Similac Pro Advance and Similac Pro Total Comfort?

Similac Pro Total Comfort makes the specific claim to be easy and gentle on your baby’s sensitive tummy. Pro Total Advance, however, does not make such claims. Interestingly, Pro Total Advance has been said to work wonders for infant constipation. So, if constipation is your baby’s issue, you may wish to give Pro Advance a shot. 

Maria Wilcox

Former instructor with an M.A. in Education turned grateful stay-at-home mama to one, I look to share helpful insights related to babies, toddlers, kids, and families for the benefit of real people just like you.

Leave a Reply

Your email address will not be published. Required fields are marked *